IndraLab

Statements

Metformin inhibits NFKB1. 3 / 3
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"Metformin combined with CO-1686 synergistically inhibited the p-IkappaB, p-IKKa and beta, p50 and p65."
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"These results suggest that metformin blocks SCC growth by dampening NFkB and mTOR signaling pathways."
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"Additionally, metformin inhibits the inflammatory response through nuclear factor kB (NFkB) inhibition via pathways involving AMPK (104, 105) ( Table 2 and Figure 1 )."
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