IndraLab

Statements


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"Mutations of KDM5C and BAP1 were significantly associated with evidence of renal vein invasion (p=0.022 and 0.046, respectively)."

sparser
"Mutations of the KDM5C and BAP1 genes were significantly associated with evidence of renal vein invasion on contrast-enhanced CT of ccRCC (p=0.022 and 0.046, respectively) The genotype of solid ccRCC differed significantly from the one of multicystic ccRCC."

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"S4G), indicating an SL interaction between BAP1 and KDM5C in UMRC6 cells.To determine whether the abovementioned SL interactions exist in patients with cancer, we checked The Cancer Genome Atlas (TCGA) data for somatic mutations targeting TSC2/LKB1 in non–small cell lung cancer and BAP1/KDM5C in ccRCC."