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MAPK1 activates COPS6. 3 / 4
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"Taken together, our study 's findings indicate that the deregulation of beta-catenin by ERK2 activated CSN6 is important for CRC development."

sparser
"Taken together, our study’s findings indicate that the deregulation of β-catenin by ERK2-activated CSN6 is important for CRC development."

sparser
"Fang et al. reported that ERK2-activated CSN6 regulates β-Trcp and stabilized β-catenin expression by blocking the ubiquitin-proteasome pathway, thereby promoting CRC development xref ."