IndraLab

Statements

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"In another study, T cells were shown to be an important source of IFN-γ in the development of a protective immune response [ 55 ] during tumorigenesis, which is consistent with our research results.In[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34237408
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"A recent study showed that ligstroside aglycon (LA), an abundant phenolic compound in extra virgin olive oil (EVOO), inhibited canonical and non-canonical activation of NLRP3 inflammasome and modulated cyclo-oxygenase-2 (COX-2) in lipopolysaccharide (LPS)-stimulated murine peritoneal macrophages."
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"These results strongly suggest that LA could inhibit inflammation by downregulating NF- kappa B/MAPK pathways and NLRP3 inflammasome activation in activated macrophages."
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"Cyclic guanosine monophosphate-phosphodiesterase type 5 (PDE5) inhibitors, fenofibrate and alpha-lipoic acid can inhibit NLRP3 inflammasome-mediated pyroptosis [140]."
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"These results indicated that LA might reduce the promotion of the NLRP3 inflammasome to inhibit inflammation."
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