IndraLab

Statements

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"Inhalation of CO significantly reduced mtDNA and IL-1beta secretion, and also decreased caspase-1 activation in response to mitochondrial damage."
30333475
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"Here, we demonstrated that CO inhibited caspase-1 activation and the secretion of IL-1beta and IL-18 in response to lipopolysaccharide (LPS) and ATP treatment in bone marrow derived macrophages."
25770182
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"Furthermore, we demonstrated that CO inhibited the cleavage of caspase-1, an inflammasome activation marker, and an upstream event, the translocation and speck formation of ASC."
36982727
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"Carbon monoxide (CO) as a byproduct of the HO-1 catalysis of hemin seems to block activation of caspase-1 through direct inhibition of its inducer molecule, NLRP3-ASC [32,33]."
36552662
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"Carbon monoxide (CO) as a byproduct of the HO-1 catalysis of hemin seems to block activation of caspase-1 through direct inhibition of its inducer molecule, NLRP3-ASC [32,33]."
36552662