IndraLab

Statements

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"EIF2alphaK1/HRI (Heme-Regulated Inhibitor) is activated by heat shock or arsenite –a known inductor of oxidative stress– [86], [87]."
20813183
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"Although arsenite also inhibits translation by activating the eIF2alpha kinase HRI, arsenite induced mRNA stabilization can be observed under HRI depleted conditions."
25446091
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"Heme depletion, arsenite-induced oxidative stress, heat shock, and osmotic stress activate the eIF2a kinase HRI, while amino acid deprivation or UV light activates GCN2 (Lu et al., 2001; Deng et al., 2002) ."
23084916