IndraLab

Statements

reach
"We showed that deleting the WW domain in Mus musculus USP8 increased DUB activity and that modeling the structure of the D. rerio ortholog (53% sequence identity) generated a homologous structure with the WW domain predicted to occupy the S1 pocket."
39214302
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"For instance, phosphorylation of human CYLD inhibits its DUB activity towards TRAF2 while phosphorylation of human USP8 inhibits its DUB activity toward EGFR (Reiley et al., 2005; Mizuno et al., 2007)."
38358795
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"For instance, phosphorylation of human CYLD inhibits its DUB activity towards TRAF2 while phosphorylation of human USP8 inhibits its DUB activity toward EGFR (Reiley et al., 2005; Mizuno et al., 2007)."
36909574
reach
"In contrast, Kasahara et al. [88] reported that EGFR kinase suppresses ciliogenesis by phosphorylating USP8 on Tyr717 and Tyr810 enhancing the deubiquitinase activity."
31845722