IndraLab

Statements

Curcumin activates KCNMA1. 7 / 7
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"Curcumin increases BK channel activity in HEK293 cells overexpressing BK (alpha+ beta1)."
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"Here, we report that curcumin up-regulates BK channel via acute modulation possibly by its direct interaction with BK channel, and through chronic effect by the increase of BK protein level."
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"We further investigated whether the activation of BK channel by curcumin is the result of the effects of curcumin on the intracellular Ca 2+, as found in previous studies [XREF_BIBR, XREF_BIBR]."
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"Curcumin increases endogenous BK channel activity in A7r5 cells."
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"In the present study, we demonstrated for the first time that curcumin up-regulates BK channel activity and protein expression level."
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"Curcumin increases BK channel activity in HEK293 cells overexpressing BK (alpha)."
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"Our study showed that curcumin stimulated BK channel activity while increasing ERK 1/2 phosphorylation, but not JNK and p38 phosphorylation."
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