IndraLab

Statements

Dronedarone inhibits KCNH2. 6 / 6
2 1 | 2 1
reach
"The half-maximal activation voltage was shifted by -6.1 mV, and HERG current block by dronedarone was voltage dependent, but not use dependent."
14517175
ctd
No evidence text available
15618689
sparser
"The L532P mutation produced an ~ 5-fold increase in the IC 50 for dronedarone inhibition of I hERG ."
21777565
tas
No evidence text available
15324906
reach
"Dronedarone blocked HERG channels with an IC50 value of 9.2 microM and a maximum tail current reduction of 85.2%."
14517175
tas
No evidence text available
21185626