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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

RNA-binding increases the amount of SCN5A. 2 / 2

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"We have shown that RNA binding protein, HuR, positively regulates SCN5A mRNA expression by protecting SCN5A mRNA from degradation in vitro."

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"Conclusions : Our study results indicate that RNA binding protein HuR can positively regulate cardiac sodium channel SCN5A expression in vivo and can reduce arrhythmia risk in heart failure."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...