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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

UCHL1 activates mTORC1. 3 / 3

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"Overall , these results suggest that UCHL1 elicits a negative effect on mTORC1 and a positive effect on mTORC2 activity in slow twitch skeletal muscle ."

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eidos

"Of note , in vivo , UCHL1 deletion does not lead to a significant and constitutive activation of mTORC1 at rest , but enhances the mTORC1 activity in response to insulin stimulation ."

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"Meanwhile, UCHL1 skmKO enhanced mTORC1 activity and reduced mTORC2 activity in soleus but not in EDL."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

UCHL1 activates mTORC1. 3 / 3

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