IndraLab

Statements

UCHL1 activates mTORC1. 3 / 3
| 2 1
eidos
"Overall , these results suggest that UCHL1 elicits a negative effect on mTORC1 and a positive effect on mTORC2 activity in slow twitch skeletal muscle ."
31356902
eidos
"Of note , in vivo , UCHL1 deletion does not lead to a significant and constitutive activation of mTORC1 at rest , but enhances the mTORC1 activity in response to insulin stimulation ."
31356902
reach
"Meanwhile, UCHL1 skmKO enhanced mTORC1 activity and reduced mTORC2 activity in soleus but not in EDL."
31356902