IndraLab

Statements

USP19 binds HIF1A. 8 / 9
2 | 1 5
sparser
"USP19 also interacts with HIF-1α, promoting its stability and an appropriate hypoxia response ( Altun et al., 2012 )."
25444757
sparser
"Usp19 interacts with the N-terminus of HIF-1α which is also where the chaperone, Heat shock protein 90 (Hsp90), associates to stabilize HIF-1α (Fig. xref a)."
34045547
biogrid
No evidence text available
22128162
biogrid
No evidence text available
22128162
sparser
"USP19 interacts with HIF-1α and stabilizes HIF-1α, regardless of the ER localization and catalytic activity of USP19 in HeLa cells."
34201062
sparser
"Another DUB, USP19, was also reported to play a regulatory role in hypoxia signaling, as USP19 could interact with the basic helix-loop-helix (bHLH)-PAS domain of HIF-1α (but not HIF-2α), and with sev[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31706510
sparser
"It has been reported that USP19 interacts with HIF-1α and thereby prevents it from degradation xref ."
29162839
reach
"It has been reported that USP19 interacts with HIF-1alpha and thereby prevents it from degradation 29."
29162839