IndraLab

Statements


USP1 increases the amount of CDKN1A. 2 / 2
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"In wild-type MEFs, Usp1 depletion increased the levels of Fancd2-Ub, TAp63, and p21 (XREF_FIG, lanes 1, 2) and enhanced OIS (XREF_FIG)."

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"In contrast, Usp1 depletion failed to induce TAp63 or p21 expression levels and only slightly induced senescence in Fancd2 (-/-) MEFs."