IndraLab

Statements


USP1 increases the amount of CDKN1A. 3 / 3
| 2 1

reach
"In contrast, Usp1 depletion failed to induce TAp63 or p21 expression levels and only slightly induced senescence in Fancd2 (-/-) MEFs."

sparser
"These results showed the P21–RB1 axis repressed USP1 transcription."

reach
"In wild-type MEFs, Usp1 depletion increased the levels of Fancd2-Ub, TAp63, and p21 (XREF_FIG, lanes 1, 2) and enhanced OIS (XREF_FIG)."