IndraLab

Statements

COPS5 increases the amount of TP53. 3 / 3
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"Our results demonstrated that CSN5 down-regulation by CSN5 siRNA or curcumin triggered significant p53 protein expression in cancer cells."
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"RNA interference (RNAi) of Jab1 restored the levels of the downregulated p53 and Smad4."
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"Furthermore, we found that downregulation of Jab1 induces the cell cycle arrest at G1 phase and upregulated the expression of p27, p53 and Bax gene."
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