IndraLab

Statements

Isoflurane inhibits FOS. 3 / 3
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"Isoflurane greatly reduced the numbers of double-labeled c-Fos/orexin-positive neurons; however, the number of c-Fos and orexin double-labeled neurons was restored after return of the righting reflex [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Isoflurane has been shown to decrease c-Fos activation in lumbar spinal cord after noxious electrical (Sommers et al., 2008) and mechanical (Jinks et al., 2002) stimulation to the hind paw."
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"Isoflurane dose dependently suppressed the c-Fos positive ratio of CRF neurons (84±16%, 25±15% and 8±12% for 0.6%, 1.0% and 1.5% isoflurane, respectively; P <0.0001)."
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