IndraLab

Statements


Methyl inhibits CTSB. 3 / 3
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"This is in contrast to bovine cathepsin B and human cathepsin L where both are more readily inhibited by the methyl, rather than the ethyl ester peptide."

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"In vivo inhibition of cathepsin B by peptidyl (acyloxy) methyl ketones."

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"In addition, CA-074 methyl ester (an inhibitor of cathepsin B) or zVAD-fmk (an inhibitor of pan-caspase) pretreatment entirely diminished these effects triggered by GEVs exposure."