IndraLab

Statements

reach
"Although the mechanism of cholesterol lowering by HCQ is not known, this drug deserves further investigation for its lipid lowering properties."
2393036
reach
"A recent systematic review and meta-analysis involving data from nine studies and 823 participants has stated that HCQ significantly reduced mean total cholesterol plasmatic levels (26.8 mg/dL; 95% CI 8.3-45.3), as well as mean LDL serum levels (24.3 mg/dL; CI95% 8.9-39.8)."
32517786
reach
"On the other hand, hydroxychloroquine has been reported to decrease total and LDL cholesterol and triglyceride concentrations [XREF_BIBR]."
20157365
reach
"Also important to its anti-atherosclerotic potential, hydroxychloroquine treatment has been shown to reduce total serum cholesterol [XREF_BIBR - XREF_BIBR]."
24672580
reach
"These results are consistent with the RNA-seq data indicating that HCQ inhibits cholesterol metabolism, suggesting that further impairing cholesterol production is synthetic lethal to HCQ treated cells."
32869031
eidos
"An Indian randomized controlled phase 3 trials showed that HCQ ( 400 mg ) as compared to pioglitazone ( 15 mg ) lowers HbA1c , LDL cholesterol levels and lead to weight loss in patients with type 2 diabetes [ 12 ] ."
32594451
reach
"A recent systematic review and meta-analysis involving data from nine studies and 823 participants has stated that HCQ significantly reduced mean total cholesterol plasmatic levels (26.8 mg/dL; 95% CI 8.3-45.3), as well as mean LDL serum levels (24.3 mg/dL; CI95% 8.9-39.8)."
32517786