IndraLab

Statements


OTUB1 leads to the ubiquitination of TRAF3. 2 / 2
| 2

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"Two close relatives of DUBA, OTUB1 and OTUB2, were shown to reduce TRAF3 ubiquitination coupled with decreased anti-viral signaling responses in Sendai virus infected HEK 293T cells."

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"These findings suggest that OTUB1 may negatively regulate virus triggered type I interferon induction and the cellular antiviral response by deubiquitinating TRAF3."