IndraLab

Statements

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"Furthermore, our results demonstrated that USP46 suppresses HCC proliferation and metastasis by inhibiting the MST1/YAP1 axis."
34029571
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"These experimental results indicate that USP46 inhibits the invasion and metastasis of hepatoma cells in vivo and in vitro ."
34029571
eidos
"Furthermore , we found that USP46 suppresses HCC cell proliferation and metastasis by inhibiting YAP1 ."
34029571
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"There are several lines of experimental evidence suggesting that USP46 inhibits cancer cell proliferation and metastasis."
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"In functional investigations, USP46 knockdown increased cell proliferation and invasiveness in vitro and in vivo whereas overexpression of USP46 decreased HCC cell proliferation and metastasis."
39410943
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"Indeed, USP46 inhibition significantly increased YAP1, as well as the proliferation and metastasis of HCC cells."
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"In addition, USP46 functions as an MST1 DUB, enhancing MST1 kinase activity to inhibit tumor development and metastasis."
39410943
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"We found that USP46 suppresses HCC cell proliferation, migration and invasion in vitro and metastasis in vivo , implying that USP46 may serve as a tumor suppressor in HCC."
34029571