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USP14 inhibits mutated SLC6A4. 1 / 1

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"Whereas reducing USP14 activity can have beneficial effects in distinct disease models, overexpression of USP14 reduces mutant HTT aggregates and counteracts cell degeneration in neural cell lines expressing expanded-polyQ HTT constructs (Hyrskyluoto et al. 2014)."

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USP14 inhibits mutated SLC6A4. 1 / 1

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