IndraLab

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USP6 binds Ccr4-Not. 2 / 2
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"We augment these preliminary findings by demonstrating that multiple components of the budding yeast Ccr4 and Not complex associate with the PRMT1 homolog, Hmt1, and that Ccr4-Not also associates with the Hmt1 substrates, Hrp1 and Nab2 in an Hmt1 methyltransferase dependent fashion XREF_BIBR, XREF_BIBR."

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"Furthermore, using genetic and biochemical approaches, we demonstrate that Ccr4-Not physically and functionally interacts with the heterogenous nuclear ribonucleoproteins (hnRNPs) Nab2 and Hrp1, and that the physical association depends on Hmt1 methyltransferase activity."