IndraLab

Statements

Gallic acid inhibits NFKB1. 7 / 7
| 7
reach
"In that study, oral GA treatment robustly increased the expression of the Drosophila orthologs of NRF2 and decreased NFkB."
38458012
reach
"However, addition of GA after CDDP treatment could reverse this increase of p65 and p50 in the nucleus."
24300974
reach
"In this study, GA significantly reduced glutamate-mediated NMDA receptor signaling and prevented the activation of NFkB as a downstream signal in the mentioned pathway (Cherng et al., 2006)."
36950127
reach
"GA has been shown to inhibit the activity of NFkB, which is essential in the pathogenesis of neurodegenerative diseases (Hwang et al., 2006)."
36950127
reach
"In another study, gallic acid also protects kidneys from interleukin-1α and interleukin-6 along with antioxidant enzymes and morphological changes ( Saleh et al., 2023 ) and a computational study was [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
38518838
reach
"Unlike Michael acceptors, a few compounds, including gallic acid ( 1 ), are able to specifically inhibit the binding of p50 to DNA, by making strong hydrogen bonds with amino acids, serine Ser 66 in p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17919455
reach
"GA is able to inhibit cell proliferation by suppressing Wnt/β-catenin signaling [113] and inhibiting the transcription factors AP-1, NF-kb, STAT1, and OCT-1 [54] in HCT-116, HCT-15, and Caco-2 cell models."
40141143