IndraLab

Statements


RPS6KB1 phosphorylates RPS6 on S235. 9 / 9
3 1 1 | 1 3
biopax:phosphositeplus
No evidence text available
phosphoelm
No evidence text available
reach
"After stimulation, S6K1 phosphorylates S6 on five serine residues (S235, S236, S240, S244, and S247) within the C-terminus [XREF_BIBR]."
phosphoelm
No evidence text available
signor
"A knockin mouse carrying mutations at all phosphorylation sites in the primary s6k substrate, ribosomal protein s6 (rps6), has provided insight into the physiological role of this protein phosphorylation event. Of the many known substrates of s6k1, it is rps6 that has been shown to be directly involved, via its phosphorylation, in controlling cell size."
reach
"The phosphorylation of rpS6 at S235 and S236 can be mediated by RSK and/or p70S6K."
phosphoelm
No evidence text available
sparser
"Similarly, p70 S6 kinase-mediated phosphorylation of ribosomal S6 at S235 and S240 was comparable between WT and Dapk −/− T cells ( xref )."
reach
"Ribosomal S6 kinase1 (S6K1), a downstream effector of mTORC1, phosphorylates ribosomal protein S6 at serine 235, 236, 240, 244 and 247 and the ratio of pS6 S235/236 / S6 was used as the functional marker of mTORC1 kinase activity 9."