IndraLab

Statements

USP10 activates SYK. 3 / 3
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reach
"Inhibition of the deubiquitinase USP10 induces degradation of SYK."
32015510
reach
"The use of USP10 inhibition to degrade SYK may additionally be explored as a potential treatment approach for other malignancies for which SYK plays an important role."
32015510
reach
"14 Yang et al. provide compelling evidence that SYK can be degraded by inhibition of USP10 leading to cell death in AML cells driven by activated SYK or mutant FLT3."
32015509