IndraLab

Statements

BAP1 inhibits cell cycle. 6 / 6
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eidos
"These results indicated that BAP1 suppressed ICC cell proliferation , cell cycle progression , and invasion via inhibiting ERK1 / 2 and JNK / c-Jun signaling pathways ."
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"These results indicated that BAP1 suppressed ICC cell proliferation, cell cycle progression, and invasion via inhibiting ERK1/2 and JNK/c-Jun signaling pathways.To further validate these findings, we used inhibitors of the ERK1/2 pathway (U0126) and JNK/c-Jun pathway (SP600125) in RBE-shBAP1 cells."
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"XREF_BIBR reported that BAP1 overexpression in the BAP1-null NCI-H226 human non-small-cell lung cancer cell line suppressed growth in DUB activity- and nuclear localization dependent manners by accelerating the cell cycle G1/S transition and inducing cell death."
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"Interestingly, there was no substantial difference in cell viability, BrdU incorporation or cell cycle profile between BAP1 deficient and control cells after stable expression of the shRNA constructs for at least 14days, indicating that the initial cell cycle inhibition caused by BAP1 depletion was transient."
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eidos
"All of these results further confirmed that BAP1 suppressed ICC cell proliferation , cell cycle progression , and invasion via inhibiting ERK1 / 2 and JNK / c-Jun signaling pathways ."
30305612
reach
"All of these results further confirmed that BAP1 suppressed ICC cell proliferation, cell cycle progression, and invasion via inhibiting ERK1/2 and JNK/c-Jun signaling pathways."
30305612