IndraLab

Statements

PRPF8 binds EFTUD2 and SNRNP200. 7 / 7
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sparser
"AAR2, ZNHIT2, and the HSP90/R2TP complex associate with the U5-specific proteins EFTUD2, PRPF8, and SNRNP200."
28515276
sparser
"Remarkably, the GFP-ZNHIT2 SILAC IP revealed a strong association of this factor with EFTUD2, PRPF8, and SNRNP200."
28515276
sparser
"Notably, depletion of the spliceosome components BRR2 and EFTUD2, which interact directly with PRPF8 to form the U5 snRNP [ xref ], most strongly phenocopy PRPF8 deficiency (Fig.  xref ; Additional file xref b, c)."
26392272
sparser
"Similarly, in humans, yeast two-hybrid and in vitro binding assays have demonstrated physical interactions between EFTUD2, SNRNP200 and PRPF8 proteins ( xref , xref ), and these interactions have been confirmed by recent cryo-EM structures of the human U4/U6."
33584830
sparser
"Importantly, our results suggest that components of Complex B, and more specifically BRR2 and EFTUD2, which interact directly with PRPF8 to form the U5 snRNP complex [ xref ], phenocopy PRPF8 most strongly."
26392272
sparser
"Specifically, TSSC4 interacts with U5-specific proteins PRPF8, EFTUD2 and SNRNP200."
34131137
reach
"In addition to the PRPF8, EFTUD2, and SNRNP200 complex, our proteomics analysis as well as previous analyses found that SNW1 was in complex with another splicing subcomplex, PRP19 complex."
25450007