IndraLab

Statements



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"While both Bufexamac and TSA treatment blocked IFN-beta promoter induction by SenV in a dose dependent manner, treatment of cells with VPA did not decrease IFN-beta promoter induction as compared to nontreated cells (XREF_FIG A)."

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"TSA treatment has been shown previously to block IFN-beta production."

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"TSA also blocked IFN-beta promoter induction by the constitutively active N-RIG construct but importantly, Bufexamac treatment did not block IFN-beta promoter induction by N-RIG."

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"Examination of additional microglial chemokine and antiviral genes (XREF_FIG and XREF_FIG, and XREF_FIG and XREF_FIG, respectively) demonstrated that IP-10, IFNbeta, IDO and viperin mRNA were all strongly inhibited by TSA and VA, whereas SB216763 had much less and insignificant effects."