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SCN11A leads to the phosphorylation of ion channel. 1 / 1
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"This occurs at least in part via EP receptor-mediated activation of intracellular kinases in the nociceptor terminal that causes phosphorylation of the nociceptive ion channel TRPV13334 and an up-regulation of Nav1.9 voltage-gated sodium channel (SCN11A)35, which is then transported to peripheral nerve terminals to contribute to increased excitability7."