IndraLab

Statements


USP17L2 activates AMOT. 2 / 2
| 2

reach
"Thus DUB3 activity can promote the stability of LATS1/2 and AMOT, which act to reduce YAP activity and increase YAP turnover, while also increasing expression of ITCH, which can promote YAP turnover."

reach
"We therefore considered the possibility that DUB3 might directly regulate the turnover of AMOT and LATS proteins."