IndraLab

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"Moreover, DSS induced the activation of mitogen activated protein kinase (MAPK) and (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome was inhibited by naringin."

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"In addition, naringin inhibited the activation of MAPK and NLRP3 inflammasome, as well as endoplasmic reticulum (ER) stress-induced autophagy [147,148]."

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"Naringin can also prevent the activation of MAPK and NLRP3 inflammasome."

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"In the Naringin treated group (NAR+VAN) there is a decreased number of NLRP3 positive cell in the SNc and CPu when compared to the Parkinson's induced group (VAN), this just shows that Naringin inhibits the activation of NLRP3 and production of Tumour Necrosis Factor alpha [21].5."

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"Naringin (NAR) inhibited microglial NLRP3 inflammasome signaling activation and pro-inflammatory factor release in rats and protected DA neuron viabilities in rats [42]."

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"Piperine, luteolin, and naringin inhibit the inflammatory response in rats by suppressing NF-κB and NLRP3 activation, thus reducing podocyte apoptosis [168, [183] [184] [185] ."