IndraLab

Statements

Thapsigargin inhibits NLRP3. 4 / 4
| 4
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"Sorbitol and thapsigargin did not suppress the activation of the NLRP3 inflammasome, whereas vincristine and paclitaxel strongly inhibited activation (XREF_FIG - XREF_FIG)."
31511697
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"Thapsigargin (an inhibitor of SERCA mediated ER Ca 2+ reuptake) and Ca 2+ -free media both partially impair NLRP3 activation, suggesting redundancy between ER and extracellular Ca 2+ pools."
25879282
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"Pretreatment or incubation in Ca -free medium with brief exposure to thapsigargin (Tg), a suppressant of the sarcoplasmic/ER Ca -ATPase (SERCA) pump, attenuates activation of the NLRP3 inflammasome."
34059091
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"Pretreatment or incubation in Ca2+-free medium with brief exposure to thapsigargin (Tg), a suppressant of the sarcoplasmic/ER Ca2+-ATPase (SERCA) pump, attenuates activation of the NLRP3 inflammasome."
34059091