IndraLab

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USP8 inhibits NFASC. 2 / 2

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"TLR4 has central role in HCC genesis by promoting the malignant transformation of epithelial cells and these data show that USP8 negatively regulates NF‐κB activation and mitophagy induction."

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"In addition, USP8 inhibition triggers MHC‐I expression and innate immune response through activating the NF‐κB signaling."

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INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP8 inhibits NFASC. 2 / 2

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