IndraLab

Statements

USP22 activates AKT. 11 / 11
| 11
reach
"XREF_FIG A, knockdown of USP22 by shRNA inhibited the AKT and MRP1 pathway compared with control shRNA cells and wild-type cells."
28417539
reach
"Previous study also showed that USP22 promotes cell cycle progression by positively regulating the PI3K and Akt pathway [XREF_BIBR]."
27145278
reach
"USP22 overexpression in gastric cancer cells induces the upregulation of SOS1 and activation of the RAS/ERK and PI3K/AKT pathways."
32063746
reach
"Western blot analysis showed that USP22 overexpression also induced activation of the RAS and ERK and PI3K and AKT pathways in SGC7901 cells and xenograft tumor tissues."
32063746
reach
"Previous studies have confirmed that USP22 can promote the biological process of NSCLC cells by regulating BMI-1 and AKT signaling pathway [XREF_BIBR]."
32294625
reach
"These results suggest that USP22 downregulation inhibits OS cells by suppressing the PI3K and Akt pathway."
27983930
reach
"We observed that USP22 could positively regulate the AKT pathway in a SIRT1 dependent manner."
28417539
reach
"Similarly, overexpression of USP22 in BEL/7402 cells activated the AKT and MRP1 pathway."
28417539
reach
"3.5 USP22 activates the AKT and MRP1 pathway depending on SIRT1 in HCC cells."
28417539
reach
"Western blot analysis showed that USP22 overexpression also induced activation of the RAS/ERK and PI3K/AKT pathways in SGC7901 cells and xenograft tumor tissues."
32063746
reach
"Moreover, SIRT1 deficiency attenuated USP22 induced activation of the AKT and MRP1 pathway in BEL7402 cells, suggesting that USP22 regulated the AKT and MRP1 pathway in a SIRT1 dependent manner."
28417539