IndraLab

Statements

PTH activates USP2. 4 / 4
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"USP2 was found to be stimulated by PTH in the bone."
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"Together, these results demonstrate that UBP41, an ubiquitin specific protease, is selectively upregulated in bone by the osteotropic agents PTH, PTHrP, and PGE2, possibly via the PKA and cAMP pathway."
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"In contrast, PTH (7-34) does not increase USP2."
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"A further study revealed that PTH ( 1-34 ) could upregulate the expression of USP2 and promote PTHR deubiquitination as well as stabilization [ 108 ] ."
30123285