IndraLab

Statements

Glucose inhibits NFKBIA. 8 / 8
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"Interestingly, HG treatment also induced increased CIKS association with IKKgamma (data not shown) Thus HG induced IkappaB-alpha degradation and NF-kappaB activation were CIKS dependent."
23085260
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"Importantly, CIKS knockdown inhibited HG induced IkappaB-alpha degradation (XREF_FIG), and p65 nuclear translocation (XREF_FIG)."
23085260
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"XREF_FIG showed that pretreatment with C66 dose-dependently reversed the HG induced degradation of IkappaBalpha (P < 0.01)."
24260158
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"Additionally, we found that TAK-242 treatment significantly suppressed the TLR4 and NF-kappaB pathway in HG induced podocytes by reducing the protein level of TLR4, p-IkappaBalpha and IkappaBalpha ratio and p-p65 and p65 ratio."
29604956
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"These data suggested that high glucose, but not osmotic pressure, induced the degradation of IkappaBalpha and activated NF-kappaB inflammatory signaling."
29038616
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"High glucose induced degradation of IkappaBalpha and activation of NF-kappaB."
24991536
eidos
"In ATDC5 cells , we could observe the high glucose up-regulated the P50 and P65 expressions and down-regulated IkappaBalpha expression , but the high glucose-activated NF-kappaB signaling could be reversed by addition of Bay ( inhibitor of NF-kappaB signaling ) ."
34934622
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"These results confirmed that administration of As-IV suppressed high glucose induced increase of TLR4 and NF-kappaB and decrease of IkappaBalpha."
30906223