IndraLab

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"For example, USP4 drives breast cancer cell invasion via Relaxin/TGF-β1/Smad2/MMP-9 (matrix metallopeptidase 9) signalling [93] and promotes hepatocellular carcinoma metastasis by enhancing TGF-β sign[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The USPs family is the largest and most important DUB family, and many of these elements are involved in the occurrence and development of multiple cancers, such as USP1, USP4, USP7, USP22, and USP28, which promote or inhibit the development and progression of colorectal, breast, and hepatocellular carcinomas via deubiquitining the hub genes of cancer-related signaling pathways [10, 11]."
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"For example, Li et al. found that USP4 can promote hepatocellular carcinoma progression via cyclophilin A stabilization and de-ubiquitination [23] ."
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