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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EZH2 inhibits BAP1. 2 / 2

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"Concomitant Bap1 and Ezh2 loss reduced myeloid progenitor expansion, reduced the proportion of Mac1 + Gr1 + myeloid cells, restored erythroid differentiation (CD71 + Ter119 +) and decreased proliferation of Bap1 and Ezh2 deficient progenitors (XREF_FIG and XREF_SUPPLEMENTARY)."

26437366

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"Ezh2 haploinsufficiency reduced, but did not abrogate, Bap1 deficient myeloproliferation (XREF_SUPPLEMENTARY) consistent with a dose dependent requirement for Ezh2."

26437366

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...