IndraLab

Statements


EZH2 inhibits BAP1. 2 / 2
| 2

reach
"Concomitant Bap1 and Ezh2 loss reduced myeloid progenitor expansion, reduced the proportion of Mac1 + Gr1 + myeloid cells, restored erythroid differentiation (CD71 + Ter119 +) and decreased proliferation of Bap1 and Ezh2 deficient progenitors (XREF_FIG and XREF_SUPPLEMENTARY)."

reach
"Ezh2 haploinsufficiency reduced, but did not abrogate, Bap1 deficient myeloproliferation (XREF_SUPPLEMENTARY) consistent with a dose dependent requirement for Ezh2."