IndraLab

Statements

USP29 increases the amount of ACSL5. 5 / 5
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"Furthermore, we found that USP29 directly interacted with ACSL5 and upregulated ACSL5 expression."
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"In contrast, USP29 deficiency significantly reduced ACSL5 protein levels in both PAOA-treated hepatocytes and the livers of HFHC diet-fed mice (Fig. 5E, F)."
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"Specifically, they found that USP29 expression is decreased in both human and mouse livers with MASLD, paralleling a reduction in ACSL5 protein levels."
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"USP29 interacts with ACSL5 and upregulates ACSL5 expression."
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"Taken together, these results suggest that USP29 markedly upregulates ACSL5 expression."
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