IndraLab

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"In summary, this study revealed that USP53 exacerbated CCI‑induced neuropathic pain, potentially via regulation of the FKBP51/RhoA/ROCK pathway."

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"Their study demonstrated that USP53 aggravated chronic compressive injury-induced neuropathic pain by activating the FKBP51/RhoA/ROCK signaling pathway.José et al. identified a variant in USP53 (p.Cys228Arg) as an underlying cause of schizophrenia [66]."