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GCGR activates USP33. 1 / 1
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reach
"When we overexpressed USP33-CH in GCGR stable HEK-293 cells, we observed a significant increase in basal ubiquitination of the GCGR, but the mutant construct did not have a similar pronounced effect in blocking deubiquitination of agonist-activated GCGRs (Fig. S5, A and B)."