IndraLab

Statements

Sertindole inhibits KCNH2. 7 / 7
4 | 3
tas
No evidence text available
21185626
reach
"Pimozide and sertindole, for example, have previously been shown to block HERG in the low nanomolar range (Rampe et al., 1998; Kang et al., 2000)."
12176106
reach
"Using patch clamp electrophysiology, we found sertindole blocked HERG currents with an IC50 value of 14.0 nM when tail currents at -40 mV were measured after a 2-sec depolarization to +20 mV."
9694935
tas
No evidence text available
12747773
tas
No evidence text available
15911273
tas
No evidence text available
19534531
reach
"A study using the HERG blocker Sertindole showed that the T wave attained minimum height just before the onset of TdP [XREF_BIBR]."
26411977