IndraLab

Statements

IKBKB binds USP18. 6 / 6
2 | 2 2
biogrid
No evidence text available
26240016
reach
"To test this prediction, we transfected 293T cells with USP18 together with IKKalpha, IKKbeta, or NEMO expression plasmids and co-immunoprecipitation and immunoblot analysis revealed that USP18 interacted with IKKalpha, IKKbeta, and NEMO (XREF_FIG)."
26240016
biogrid
No evidence text available
26240016
sparser
"To determine the mechanism of the USP18 and IKKβ interaction, we generated deletion mutants encompassing the amino-terminal kinase domain (KD), leucine zipper domain (LZ), and a C-terminal helix-loop-helix (HLH) domain of IKKβ ( xref ), and performed immunoprecipitation to test their ability to interact with USP18."
26240016
reach
"To determine the mechanism of the USP18 and IKKbeta interaction, we generated deletion mutants encompassing the amino-terminal kinase domain (KD), leucine zipper domain (LZ), and a C-terminal helix-loop-helix (HLH) domain of IKKbeta (XREF_FIG), and performed immunoprecipitation to test their ability to interact with USP18."
26240016
sparser
"Similar to full-length IKKβ, all mutated domains could interact with USP18 ( xref ), suggesting that IKKβ may not be the direct target of USP18."
26240016