IndraLab

Statements


3 | 2

sparser
"YOD1 interacts with MAVS through its ubiquitin regulatory X and ZF domains and removes K63-linked polyubiquitin chains on MAVS, thereby inhibiting the formation of MAVS prion-like aggregates ( xref )."

sparser
"After viral infection, OTUD2 (also known as YOD1) interacts with MAVS through its UBX and Znf domains at the mitochondria, followed by the cleavage the K63-linked ubiquitin chains of MAVS that induced the abrogation of MAVS oligomerization to attenuate the IFN production [ xref ]."

No evidence text available

No evidence text available

No evidence text available