IndraLab

Statements

USP47 deubiquitinates YAP1. 3 / 3
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"The deubiquitination enzymes ubiquitin specific peptidase 10 (USP10), ubiquitin specific peptidase 47 (USP47), OUT deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2), and eukaryotic translation initiation factor 3 subunit H (EIF3H) deubiquitinated YAP1 to maintain protein stability [61, 62, 63]."
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"Another three DUBs, ubiquitin carboxyl-terminal hydrolase 10 (USP10), otubain-2 (OTUB2) and ubiquitin carboxyl-terminal hydrolase 47 (USP47) deubiquitinate YAP/TAZ, playing important roles in hepatocellular carcinoma, breast cancer and colorectal cancer, respectively21 32 33."
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"For instance, USP9X, ubiquitin-specific peptidase 47 (USP47), and OTU deubiquitinase ubiquitin aldehyde binding 1 (OTUB1) directly deubiquitinate YAP [33–35]."
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