IndraLab

Statements

CK1δ phosphorylates USP46. 4 / 4
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sparser
"CK1δ binds and phosphorylates USP46 at Thr209, Ser351 and Ser354."
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sparser
"We next investigated whether CK1δ could phosphorylate USP46."
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sparser
"These results suggest that CK1δ directly phosphorylates USP46 and activates its deubiquitinase activity toward NRAS Q61R."
39572526
sparser
"As shown in Supplementary Fig.  xref , CK1δ significantly increased the phosphorylation of USP46 WT assessed by anti-p-Ser and anti-p-Thr antibodies, whereas the 3A mutant could largely decrease such phosphorylation events."
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