IndraLab

Statements



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"[Chinfloxacin hydrochloride inhibits HERG potassium channel at open state]."

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"In addition, the electrophysiology study indicated that ET-26 HCl and etomidate inhibited the hERG at a supra-therapeutic concentration."

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"Considering that K + channel has relatively high selectivity for the permeating ion, K + rather than Na +, Ca 2+, and Cl -, the MeOH extract at relatively high concentrations of 100 and 300 microg/mL, could perturb the ion-selectivity of HERG channel by inducing non specific membrane permeabilization or membrane leakage."