IndraLab

Statements


PLA1A activates KCNH2. 1 / 1
| 1

reach
"In contrast, when we employed a minigene construct that could generate the full-length hERG mRNA and protein, and importantly, could undergo RNA splicing, the same mutation caused a marked reduction in mutant protein levels and hERG current, a finding consistent with degradation of mutant mRNA by NMD."