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USP20 deubiquitinates RAD17. 2 / 2

1 | 1

"Similar to Chk1 and <span class="match term1">Rad17</span>, which enhance recombinational repair of collapsed replication forks, we demonstrate that <span class="match term0">USP20</span> depletion impairs DNA double strand break repair by homologous recombination."

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"ATM/ATR-mediated phosphorylation of USP20 does not affect its DUB activity; rather, this USP20 phosphorylation enhances the association of USP20 with Rad17 and thereby enhances USP20-mediated deubiquitination of Rad17 (41)."

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USP20 deubiquitinates RAD17. 2 / 2

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