IndraLab

Statements

TRPM channels activates KCNH2. 1 / 1

| 1

reach

"TRPM channels in islets are thought to be key players in the regulated release of insulin XREF_BIBR, XREF_BIBR and TRPM3 in particular is known to mediate the regulated uptake of zinc from the extracellular space mouse beta cells 38, when engaged by the neurosteroid hormone pregnenolone sulphate, to potentiate insulin secretion 39, and activate an Erg-1 dependent transcriptional pathway leading to PDX1, and in turn insulin, up-regulation 40."

29070792

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

TRPM channels activates KCNH2. 1 / 1

INDRA sources:

Databases

Reading