IndraLab

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OTUB1 ubiquitinates RACK1. 3 / 3
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"Therefore, we hypothesize that OTUB1 may take part in the ubiquitination of RACK1, thus affecting macrophage polarization and ultimately contributing to the progression of OSCC.To prove the above hypo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Our data also demonstrated that OTUB1 inhibited macrophage M1 polarization in the tumor microenvironment by inhibiting the ubiquitination of RACK1, thereby contributing to OSCC progression."
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"Further studies conclusively showed that OTUB1 decreased macrophage M1 polarization in the OSCC microenvironment by inhibiting the ubiquitination of RACK1, thereby promoting the development of OSCC."
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